Any other recommendations? Makes/models that fit the bill?
Here are my qualifications:
- Fits a 17" MacBook Pro. Built-in laptop compartment preferable.
- Versatile. Works well on scooter and bicycle but also under the seat in front of me on an airplane.
- Voluminous but not bulky. Kind of like the Tardis.
- Easy access. External and side pockets a plus. (Rolltops may be immediately disqualified for this reason.)
- Durable.
- Comfortable.
- Reasonably priced. (Under $200 MSRP. I will probably not be paying full retail for any, so clearance or availability on eBay are pluses.)
- Not ugly.
- Bonus points for reflective elements, any kind of external straps or loops for hanging and attaching helmets and accessories.

Herschel Little America: I really WANT this to be perfect, but it isn't. In particular, I don't expect the leather straps to last. Aesthetically, a winner. Also, can be found for under $100.

Osprey Metron 35: Sites are divided on whether or not this will fit a 17" laptop. Great reputation for durability.

North Face Mondaze: TOO big? 30L!

North Face Pre-Hab: at 28L, almost as large. Nice features. (I mean the backpack, you pervs.)
<iframe width="560" height="315" src="http://www.youtube.com/embed/ZRNWVS_wON0" frameborder="0" allowfullscreen></iframe>
Think I'll head to the North Face store soon.

Timbuk 2 Phoenix: The big strap is problematic. A friend says it hangs to her knees when unbuckled.

Chrome Cardiel Fortnight: This is almost kind of sexy, for a backpack. Larger than photo suggests. On the pricey side. Might be worth it. No laptop sleeve. Need to check dimensions.

Dakine Vault 23/25: Oh, so close. Maybe. I currently have a Dakine Campus and it's not holding up well. Anyone had a Dakine for several years?

Ogio Renegade RSS: This may win on features in its price range. Suspension laptop sleeve! One of my grips with many is that the laptop can hit the ground hard when you set your pack down. Tons of access and pockets, many with extra padding. My former fave was an Ogio Fugitive, destroyed in a crash (though I still bike with it). The cons? Aesthetics (over-branded). No external straps or places for lights or reflective add-ons.
Disqualified:
Mission Workship Arkiv R2/R6: The ultimate if not for two things (laptop size too small, would cost me $$$$ in the configuration I'd want).
Timbuk 2 HAL: Overly complex.

Timbuk 2 Uptown: Fails on durability.
The Flying Unicorn: Looks like a Herschel Little America, has the features of the Ogio Renegade, the sex appeal of the Chrome Cardiel, and the durability of the Osprey Metron 35.
By the way, what I'm keeping:
One Tactical Bail Out Bag (BOB). The black one.
A small bag or sling for minimal carrying. The man bag. The Murse. Maybe something like a Herschel Eighteen, worn as a sling so I can get to camera, etc. while on bike or scooter. NOT a fanny pack!
My semi-trashed Ogio Fugitive, which I use for biking now. It's a pain to swap all my gear from one pack to another.
Getting rid of:
Timbuk 2 Messenger. Older one from when the company was young. Plain tan all over, kinda dirty. Was going to hold all my rally patches, but sewing through that waterproof-lined material is too much of a PITA.
Timbuk 2 mini bag. Camo with big, super reflective pink stripe down the middle. May keep this in lieu of man bag/sling (above).
Corazzo Messenger: Very nice, but torn pen pocket.
Prima Messenger: Virtually unused.
Dakine Campus: Two holes. Losing its shape. Adios.
Another messenger: Has a cool "EXIT" graphic. Doesn't get used enough.